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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and proposals for monitoring. Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone improve human platelet thromboxane A2 receptor density and aggregation responses.
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We report a case of an acute ST-segment elevation myocardial infarction in a patient with conventional cardiac risk components utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, probably secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the proper coronary artery. Physicians and sufferers should pay consideration to the medical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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